Completed Puzzles Puzzle PZ9 Results

Description
5-hydroxytryptophan aptamer
RNA sequence (5' to 3')
GGACACUGAUGAUCGCGUGGAUAUGGCACGCAUUGAAUUGU UGGACACCGUAAAUGUCCUAACACGUGUCC
Experimental structure(s)
References

E. B. Porter, J. T. Polaski, M M. Morck and R. T. Batey (2017) Recurrent RNA motifs as scaffolds for genetically encodable small-molecule biosensors. Nature Chemical Biology volume 13: 295–301

PDB ID:
Opening date:
19 Oct 2020, 23:24
Closing date (Human category):
19 Oct 2020, 23:24

Hide or show column:

# Group (User) Model(s) Category Clashscore
DI
INF all
INF nwc
INF stacking
INF wc
MCQ
P-Value
RMSD
Details
1 Chen Group (Chen ) 7 Human 18.090 8.713 0.695 0.405 0.679 0.872 18.730 0.000 6.058
2 Bujnicki Group (Bujnicki ) 3 Human 1.320 8.998 0.689 0.533 0.718 0.685 24.470 0.000 6.197
3 Bujnicki Group (Bujnicki ) 4 Human 1.320 8.998 0.689 0.533 0.718 0.685 24.470 0.000 6.197
4 Bujnicki Group (Bujnicki ) 5 Human 1.320 8.998 0.689 0.533 0.718 0.685 24.470 0.000 6.197
5 Chen Group (Chen ) 3 Human 29.520 9.071 0.704 0.570 0.667 0.872 18.630 0.000 6.386
6 Chen Group (Chen ) 2 Human 26.440 8.763 0.730 0.615 0.708 0.850 18.110 0.000 6.393
7 Chen Group (Chen ) 5 Human 33.040 8.644 0.740 0.615 0.716 0.872 20.100 0.000 6.401
8 Chen Group (Chen ) 4 Human 23.780 8.860 0.731 0.615 0.709 0.850 19.350 0.000 6.478
9 Chen Group (Chen ) 8 Human 65.880 8.813 0.738 0.615 0.718 0.850 16.360 0.000 6.503
10 Chen Group (Chen ) 1 Human 34.760 9.107 0.715 0.615 0.691 0.830 18.770 0.000 6.509
11 Chen Group (Chen ) 6 Human 64.670 9.756 0.676 0.570 0.663 0.763 20.130 0.000 6.599
12 Das Group (Das ) 2 Human 2.200 11.184 0.690 0.522 0.667 0.850 17.310 0.000 7.719
13 Das Group (Das ) 5 Human 4.840 10.326 0.750 0.704 0.730 0.830 17.520 0.000 7.749
14 Das Group (Das ) 3 Human 15.850 11.937 0.699 0.483 0.694 0.850 18.780 0.000 8.338
15 Das Group (Das ) 6 Human 9.250 11.840 0.727 0.640 0.711 0.810 19.290 0.000 8.604
16 Das Group (Das ) 1 Human 4.840 11.645 0.743 0.704 0.699 0.878 19.310 0.000 8.654
17 Das Group (Das ) 7 Human 9.250 12.652 0.702 0.455 0.698 0.850 19.260 0.000 8.880
18 Ding Group (Ding ) 5 Human 14.050 12.997 0.687 0.000 0.690 0.867 23.990 0.000 8.930
19 Ding Group (Ding ) 3 Human 10.540 14.286 0.629 - 0.591 0.867 23.300 0.000 8.982
20 Das Group (Das ) 4 Human 3.520 13.023 0.728 0.585 0.723 0.830 17.010 0.000 9.485
21 Ding Group (Ding ) 7 Human 9.660 13.897 0.690 - 0.663 0.923 24.850 0.000 9.586
22 Ding Group (Ding ) 1 Human 14.930 16.766 0.572 0.000 0.507 0.867 23.400 0.000 9.587
23 Das Group (Das ) 9 Human 3.080 14.275 0.683 0.477 0.680 0.793 18.030 0.000 9.743
24 Ding Group (Ding ) 2 Human 14.050 15.694 0.623 0.000 0.604 0.867 23.810 0.000 9.785
25 Ding Group (Ding ) 4 Human 12.300 15.320 0.641 0.000 0.625 0.850 22.960 0.000 9.816
26 Ding Group (Ding ) 9 Human 10.540 13.758 0.720 0.000 0.745 0.858 24.600 0.000 9.911
27 Das Group (Das ) 8 Human 2.200 14.451 0.727 0.603 0.698 0.872 20.200 0.000 10.501
28 Ding Group (Ding ) 8 Human 14.050 17.227 0.644 0.000 0.657 0.805 23.480 0.000 11.101
29 Ding Group (Ding ) 10 Human 8.780 18.317 0.608 0.000 0.557 0.900 24.090 0.000 11.134
30 Ding Group (Ding ) 6 Human 10.540 19.740 0.611 0.000 0.571 0.923 23.300 0.000 12.062
31 Dokholyan Group (Dokholyan ) 4 Human 4.830 38.573 0.501 - 0.442 0.746 26.430 0.004 19.342
32 Dokholyan Group (Dokholyan ) 1 Human 7.910 37.694 0.535 - 0.489 0.763 29.300 0.016 20.162
33 Dokholyan Group (Dokholyan ) 3 Human 6.590 42.095 0.531 - 0.477 0.776 27.040 0.174 22.353
34 Dokholyan Group (Dokholyan ) 2 Human 7.030 44.444 0.572 - 0.542 0.781 26.200 0.780 25.434
Metric Webserver category Human category
Median Mean Median Mean
Clashscore - - 10.100 14.734
DI - - 12.825 15.614
INF all - - 0.690 0.671
INF nwc - - 0.480 0.335
INF stacking - - 0.685 0.652
INF wc - - 0.850 0.829
MCQ - - 21.580 21.678
P-Value - - 0.000 0.029
RMSD - - 8.905 9.935

Result visualization for different evaluation measures

Violin plot for Clashscore
Violin plot for DI
Violin plot for INF all
Violin plot for INF nwc
Violin plot for INF stacking
Violin plot for INF wc
Violin plot for MCQ
Violin plot for P-Value
Violin plot for RMSD