Completed puzzles (34)
Puzzle PZ23
Description
Mango-III aptamer
RNA sequence (5' to 3')
GUACGAAGGAAGGUUUGGUAUGGGGUAGUUGUCGUAC
Experimental structure(s)
solutionPZ23.pdb
References

R. J. Trachman 3rd, A. Autour, S. C. Y. Jeng, A. Abdolahzadeh, A. Andreoni, R. Cojocaru, R. Garipov, E. V. Dolgosheina, J. R. Knutson, M. Ryckelynck, P. J. Unrau and A. R. Ferré-DAmaré (2019) Structure and functional reselection of the Mango-III fluorogenic RNA aptamer. Nature Chemical Biology, 15(5): 472-479

PDB ID:
6e8u
Opening date:
19 Nov 2018, 23:24
Closing date (Human category):
10 Dec 2018, 23:24
Closing date (Webserver category):
21 Nov 2018, 23:24
Puzzle PZ22
Description
Hatchet Ribozyme
RNA sequence (5' to 3')
UUACUGUGAGAAUCAGUAACAAACAUGUGGGGCUUAUAU CUAAUCGAAAGAUUAGUAUUAGUGCAGAC GUUAAAACCAUGUC
Experimental structure(s)
solutionPZ22.pdb
References

L. Zheng, C. Falschlunger, K. Huang, E. Mairhofer, S. Yuan, J. Wang, D. J. Patel, R. Micura and A. Ren (2019) Hatchet ribozyme structure and implications for cleavage mechanism. Proc Natl Acad Sci U S A., 116(22): 10783-10791

PDB ID:
6jq5
Opening date:
19 Nov 2018, 22:24
Closing date (Human category):
17 Dec 2018, 23:24
Closing date (Webserver category):
21 Nov 2018, 23:24
Puzzle PZ21
Description
Guanidine III Riboswitch
RNA sequence (5' to 3')
CCGGACGAGGUGCGCCGUACCCGGUCAGGACAAGACGGCGC
Experimental structure(s)
solutionPZ21.pdb solutionPZ21_1.pdb solutionPZ21_2.pdb
References

L. Huang, J. Wang, T. J. Wilson and D. M. J. Lilley (2017) Structure of the Guanidine III Riboswitch. Cell Chem Biol, 2017 24(11): 1407-1415.e2.

PDB ID:
5nwq
Opening date:
12 Jun 2017, 23:24
Closing date (Human category):
03 Jul 2017, 23:24
Closing date (Webserver category):
14 Jun 2017, 23:24
Puzzle PZ20
Description
Another Twister Sister ribozyme
RNA sequence (5' to 3')
ACCCGCAAGGCCGACGGC-GCCGCCGCUGGUGCAAGUCCAGCCACGCUUC GGCGUGGGCGCUCAUGGGU
Experimental structure(s)
solutionPZ20.pdb solutionPZ20_1.pdb solutionPZ20_2.pdb solutionPZ20_3.pdb
References

L. Zheng, E. Mairhofer, M. Teplova, Y. Zhang, J. Ma, D. J. Patel, R. Micura and A. Ren (2017) Structure-based insights into self-cleavage by a four-way junctional twister-sister ribozyme. Nature Communications, 8: 1180

PDB ID:
5y85
Opening date:
17 May 2017, 23:24
Closing date (Human category):
14 Jun 2017, 23:24
Closing date (Webserver category):
19 May 2017, 23:24
Puzzle PZ19
Description
One Twister Sister robozyme
RNA sequence (5' to 3')
GCAGGGCAAGGCCCAGUCCCGUGCAAGCCGGGACCGCCCC- GGGGCGCGGCGCUCAUUCCUGC
Experimental structure(s)
solutionPZ19.pdb
References

Y. Liu, T. J. Wilson and D. M. J. Lilley (2017) The structure of a nucleolytic ribozyme that employs a catalytic metal ion. Nature Chemical Biology, 13: 508–513

PDB ID:
5t5a
Opening date:
24 Oct 2016, 23:24
Closing date (Human category):
10 Nov 2016, 23:24
Closing date (Webserver category):
26 Oct 2016, 23:24