Completed puzzles (34)
Puzzle PZ9
Description
5-hydroxytryptophan aptamer
RNA sequence (5' to 3')
GGACACUGAUGAUCGCGUGGAUAUGGCACGCAUUGAAUUGU UGGACACCGUAAAUGUCCUAACACGUGUCC
Experimental structure(s)
solutionPZ9.pdb
References

E. B. Porter, J. T. Polaski, M M. Morck and R. T. Batey (2017) Recurrent RNA motifs as scaffolds for genetically encodable small-molecule biosensors. Nature Chemical Biology volume 13: 295–301

PDB ID:
5kpy
Opening date:
19 Oct 2020, 23:24
Closing date (Human category):
19 Oct 2020, 23:24
Puzzle PZ8
Description
SAM riboswitch.
RNA sequence (5' to 3')
GGAUCACGAGGGGGAGACCCCGGCAACCUGGGACGGACACCCAAGGUGCUCACA CCGGAGACGGUGGAUCCGGCCCGAGAGGGCAACGAAGUCCGU
Experimental structure(s)
solutionPZ8.pdb
References

J. J. Trausch, Z. Xu, A. L. Edwards, F. E. Reyes, P. E. Ross, R. Knight and R.T. Batey (2014) Structural basis for diversity in the SAM clan of riboswitches. PNAS.111(18): 6624-9.

PDB ID:
4l81
Opening date:
19 Oct 2020, 23:24
Closing date (Human category):
19 Oct 2020, 23:24
Puzzle PZ7
Description
Varkud satellite ribozyme.
RNA sequence (5' to 3')
GCGCUGUGUCGCAAUCUGCGAAGGGCGUCGUCGGCCCGAGCGGUAGUAAGCAGG GAACUCACCUCCAAUGAAACACAUUGUCGUAGCAGUUGACUACUGUUAUGUGAU UGGUAGAGGCUAAGUGACGGUAUUGGCGUAAGCCAAUACCGCGGCACAGCACAA GCCCGCUUGCGAGAUUACAGCGC
Experimental structure(s)
solutionPZ7.pdb solutionPZ7_1.pdb
References

N. B. Suslov, S. DasGupta, H. Huang, J. R. Fuller, D. M. J. Lilley, P. A. Rice and J. A. Piccirilli. (2015). Crystal structure of the Varkud satellite ribozyme. Nature Chemical Biology 11: 840–846.

PDB ID:
4r4v
Opening date:
19 Oct 2020, 23:24
Closing date (Human category):
19 Oct 2020, 23:24
Puzzle PZ6
Description
adenosylcobalamin riboswitch.
RNA sequence (5' to 3')
CGGCAGGUGCUCCCGACCCUGCGGUCGGGAGUUAAAAGGGAAGCCGGUGCAAGU CCGGCACGGUCCCGCCACUGUGACGGGGAGUCGCCCCUCGGGAUGUGCCACUGG CCCGAAGGCCGGGAAGGCGGAGGGGCGGCGAGGAUCCGGAGUCAGGAAACCUGC CUGCCG
Experimental structure(s)
solutionPZ6.pdb
References

A. Peselis and A. Serganov (2012). Structural insights into ligand binding and gene expression control by an adenosylcobalamin riboswitch. Nature Structural and Molecular Biology 19 (11): 1182-1184.

PDB ID:
4gxy
Opening date:
19 Oct 2020, 23:24
Closing date (Human category):
19 Oct 2020, 23:24
Puzzle PZ5
Description
group I intron.
RNA sequence (5' to 3')
CAUCCGGUAUCCCAAGACAAUCUCGGGUUGGGUUGGGAAGUAUCAUGGCUAAUC ACCAUGAUGCAAUCGGGUUGAACACUUAAUUGGGUUAAAACGGUGGGGGACGAU CCCGUAACAUCCGUCCUAACGGCGACAGACUGCACGGCCCUGCCUCAGGUGUGU CCAAUGAACAGUCGUUCCGAAAGGAAG
Experimental structure(s)
solutionPZ5.pdb solutionPZ5_1.pdb solutionPZ5_2.pdb
References

M. Meyer, H. Nielsen, V. Oliéric, P. Roblin, S. D. Johansen, E. Westhof and B. Masquida (2014). Speciation of a group I intron into a lariat capping ribozyme. PNAS.111(21): 7659-64.

PDB ID:
4p9r
Opening date:
19 Oct 2020, 23:24
Closing date (Human category):
19 Oct 2020, 23:24