Completed puzzles (34)
Puzzle PZ13
Description
ZMP Riboswitch.
RNA sequence (5' to 3')
GGGUCGUGACUGGCGAACAGGUGGGAAACCACCGGGGAGCGACCCCGGCAUCGA UAGCCGCCCGCCUGGGC
Experimental structure(s)
solutionPZ13.pdb solutionPZ13_1.pdb solutionPZ13_2.pdb
References

J. J. Trausch, J. G. Marcano-Velázquez, M. M. Matyjasik and R. T. Batey (2015) Metal Ion-Mediated Nucleobase Recognition by the ZTP Riboswitch. Chem Biol. 22(7): 829-37.

PDB ID:
4xw7
Opening date:
19 Oct 2020, 23:24
Closing date (Human category):
19 Oct 2020, 23:24
Puzzle PZ12
Description
ydaO riboswitch.
RNA sequence (5' to 3')
AUCGCUGAACGCGGGGGACCCAGGGGGCGAAUCUCUUCCGAAAGGAAGAGUAGG GUUACUCCUUCGACCCGAGCCCGUCAGCUAACCUCGCAAGCGUCCGAAGGAGAA AAA
Experimental structure(s)
solutionPZ12.pdb
References

A. Ren, D. J. Patel (2014) c-di-AMP binds the ydaO riboswitch in two pseudo-symmetry-related pockets. Nat Chem Biol. 10(9): 780-6.

PDB ID:
4qlm
Opening date:
19 Oct 2020, 23:24
Closing date (Human category):
19 Oct 2020, 23:24
Puzzle PZ11
Description
7SK
RNA sequence (5' to 3')
GGGAUCUGUCACCCCAUUGAUCGCCUUCGGGCUGAUCUGGCUGG CUAGGCGGGUCCC
Experimental structure(s)
solutionPZ11.pdb solutionPZ11_1.pdb solutionPZ11_NMR.pdb
References

D. Martinez-Zapien, P. Legrand, A. G. McEwen, F. Proux, T. Cragnolini, S. Pasquali and A. C. Dock-Bregeon (2017) The crystal structure of the 5΄ functional domain of the transcription riboregulator 7SK. Nucleic Acids Res. 45(6): 3568-3579.
S. Bourbigot, A. C. Dock-Bregeon, P. Eberling, J. Coutant, B. Kieffer and I. Lebars (2016) Solution structure of the 5-terminal hairpin of the 7SK small nuclear RNA. RNA. 2016 22(12): 1844-1858.

PDB ID:
5lys
Opening date:
19 Oct 2020, 23:24
Closing date (Human category):
19 Oct 2020, 23:24
Puzzle PZ10tBox
Description
T-box riboswitch
RNA sequence (5' to 3')
UGCGAUGAGAAGAAGAGUAUUAAGGAUUUACUAUGAUUAGCGACUCUAGGAUAG UGAAAGCUAGAGGAUAGUAACCUUAAGAAGGCACUUCGAGCA
Experimental structure(s)
solutionPZ10tBox.pdb solutionPZ10tBox_1.pdb
References

J. Zhang and A. R. Ferré-DAmaré (2013) Co-crystal structure of a T-box riboswitch stem I domain in complex with its cognate tRNA. Nature 500: 363-366.

PDB ID:
4lck
Opening date:
19 Oct 2020, 23:24
Closing date (Human category):
19 Oct 2020, 23:24
Puzzle PZ10
Description
tRNA complex
RNA sequence (5' to 3')
GCGGAAGUAGUUCAGUGGUAGAACACCACCUUGCCAAGGUGGGGGUCGCGGGUU CGAAUCCCGUCUUCCGCUCCA
Experimental structure(s)
solutionPZ10.pdb solutionPZ10_1.pdb
References

J. Zhang and A. R. Ferré-DAmaré (2013) Co-crystal structure of a T-box riboswitch stem I domain in complex with its cognate tRNA. Nature 500: 363-366.

PDB ID:
4lck
Opening date:
19 Oct 2020, 23:24
Closing date (Human category):
19 Oct 2020, 23:24